(informal)have common sense
(非正式)有见识；头脑清醒
(informal)be slightly eccentric or mentally disturbed
(非正式)古怪；神经不正常
(informal)exert strong psychological pressure on (someone) so as to intimidate them into doing something
(非正式)给（某人）施加心理压力；强迫（某人）
(informal)an additional degree of pressure or hardship added to a situation that is already extremely difficult to bear
(非正式)困难情况下又添加的压力；雪上加霜
(informal)exert strong pressure on someone
(非正式)施加压力
(informal)treat someone unfairly; cheat or swindle someone
(非正式)歧视；欺骗
(informal)cause someone to be emotionally or mentally disturbed
(非正式)使受刺激；使紧张
this job can really screw you up.
这份工作真能使你精神紧张。
crush a piece of paper or fabric into a tight mass
把纸（或织物）揉成一团
(informal)cause something to fail or go wrong
(非正式)使失败；使出问题
why are you trying to screw up your life?.
你为什么要把生活搞得一团糟？。
summon up one's courage
鼓起勇气
now Stephen had to screw up his courage and confess.
现在斯蒂芬不得不鼓起勇气承认。
&I{Slang} To act or fool around aimlessly or in a confused way and accomplish nothing.
&I{【俚语】} 虚度：无目的地或以糊涂的方式行动或干傻事，什么也没有完成
&I{Vulgar} &I{Slang} To be sexually promiscuous.
&I{【粗俗用语】} &I{【俚语】} 乱交
To muster or summon up
召集或号召
screwed up my courage.
鼓起我的勇气
&I{Slang} To make a mess of (an undertaking).
&I{【俚语】} 把（事业）弄糟
&I{Slang} To injure; damage
&I{【俚语】} 伤害；破坏
Lifting those boxes really screwed up my back.
抬这些箱确实令我的背部受到损伤
&I{Slang} To make neurotic or anxious.
&I{【俚语】} 使心情烦乱或紧张
To behave in an eccentric manner.
行为非常古怪
To be insane.
神经不正常